Activity of Corylus avellana seed oil in letrozole-induced polycystic ovary syndrome model in rats
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منابع مشابه
P-184: Effects of Licorice Hydroalcoholic Root Extract on Letrozole-Induced Polycystic Ovary Syndrome in Mouse
Background: Polycystic ovary syndrome (PCOS) is multifaceted and includes reproductive, metabolic, and general health disorders, so employing different animal models is needed to study the syndrome. Use of an aromatase inhibitor, letrozole, on adult female rats produces a phenotype remarkably similar to that of PCOS. Licorice has been used in treating women infertility for thousands of years. L...
متن کاملThe Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome
Women with polycystic ovary syndrome (PCOS) have reproductive and metabolic abnormalities that result in an increased risk of infertility, diabetes and cardiovascular disease. The large intestine contains a complex community of microorganisms (the gut microbiome) that is dysregulated in humans with obesity and type 2 diabetes. Using a letrozole-induced PCOS mouse model, we demonstrated signific...
متن کاملEffect of Berberine on the Levels of Sex Hormones in Polycystic Ovary Syndrome-Induced by Letrozole in Adult Female Wistar Rats
Background and Objectives: Berberine is a yellow alkaloid, which is found in root, rhizome, skin, and stem of many plants, including barberry, turmeric, and poppy. Berberine has anti-inflammatory, anti-bacterial, and anti-viral properties. In the present study, the protective effect of berberine on letrozole-induced Polycystic Ovary Syndrome (PCOS), was investigated in adult female Wistar rats....
متن کاملChanges of The Uterine Tissue in Rats With Polycystic Ovary Syndrome Induced by Estradiol Valerate
Objective : Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. Reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. In this study, the effect of PCOS induction was studied using estradiol valerate. MaterialsAndMethods Adult ...
متن کاملLetrozole versus clomiphene for infertility in the polycystic ovary syndrome.
BACKGROUND Clomiphene is the current first-line infertility treatment in women with the polycystic ovary syndrome, but aromatase inhibitors, including letrozole, might result in better pregnancy outcomes. METHODS In this double-blind, multicenter trial, we randomly assigned 750 women, in a 1:1 ratio, to receive letrozole or clomiphene for up to five treatment cycles, with visits to determine ...
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ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2016
ISSN: 0102-695X
DOI: 10.1016/j.bjp.2015.09.009